Research and Resources


Our research spans a broad range of topics relevant to the biopharma industry, and has led to several peer-reviewed articles. For more information about our research activities or reprints of paywalled papers, contact us at And, don't forget to scroll to the bottom of the page for some of our "evergreen" resources!

Screen Shot 2017-06-16 at 12.15.54 PM.png

the myth of "leaner and meaner" pharma

Drug makers commonly tout layoffs and reorganizations as tools to boost productivity. But have they really improved the "return on talent"? We examined total headcount and profit per employee to see if these efforts are paying off.


Value-based healthcare - the customer perspective

Warren Buffett famously said that, "Price is what you pay, value is what you get." But how do purchasers of medical devices and drugs perceive value? We asked hospital CFOs and other financial stakeholders how they decide whether or not to adopt new products in a capitated payment setting, the inpatient operating room.


historical trends in pharma R&D spending

Prior analyses of pharma R&D and SG&A spending have focused on each category as a percent of revenues. In this work, we instead look at historical trends over time to discover how drug companies choose to allocate resources, particularly when revenues are pressured.



Pharma regulatory strategy would be radically transformed if the FDA were compelled to automatically consider drugs already approved in other countries for market approval. In this cohort analysis, we measure how U.S. patients could be affected by this proposed policy.

fig - launch curve.png

Drug launch curves in the modern era

The historical view of prototypical drug launches is based on 30-year-old work focused on cardiovascular medicines. Here, we update those data and provide a revised view of ramp rates of "pioneer" and "follower" drugs.

fig - fin adap trials.jpg


Clinical development planning and financial analysis are traditionally conducted in separate silos. In this piece, we illustrate the benefits that drug companies can reap by integrating these activities.



Here are some "evergreen" resources we've developed for biomedical innovators - for more information, please contact us at


Pitch deck tips for biotech and medtech start-ups

A Google search for "biotech pitch decks" returns lots of hits - but many of them are irrelevant to drug and device newcos. Have no fear - we've got a list of the best resources for you.


Academic-industry R&D collaborations

Many pharma companies are fostering external collaborations via "open innovation" initiatives. We've compiled a directory of industry programs that provide compounds, resources, and funding to academic investigators.